产品货号：
Z34756
中文名称：
MEK3/6抗体
英文名称：
Anti-MEK3/6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MEK3/6 Antibody |
| 指标别名 | MEK6;MKK6;MAPKK6;PRKMK6;SAPKK3;MAP2K6;MEK3;MAP kinase kinase 3;MAPKK3;MAPK/ERK kinase 3 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,FCM |
| 基因名称 | MAP2K3/MAP2K6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human MEK3/MEK6 |
| 实际分子量 | 39KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene.The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family.This kinase is activated by mitogenic and environmental stress,and participates in the MAP kinase-mediated signaling cascade.It phosphorylates and thus activates MAPK14/p38-MAPK.And this kinase can be activated by insulin,and is necessary for the expression of glucose transporter.Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase,which thus leads to the constitutive activation of MAPK14,and confers oncogenic transformation of primary cells.Rampoldi et al.(1997) localized the MAP2K3 gene to 17q11.2. |
| Uniprot ID | P46734/P52564 |
| 基因名全称 | Dual specificity mitogen-activated protein kinase kinase 3 |
| 推荐稀释比 | Western blot (WB) 1:400～800 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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